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Br J Hosp Med (Lond) ; 82(2): 1-4, 2021 Feb 02.
Article in English | MEDLINE | ID: covidwho-1110766

ABSTRACT

The UK government recently decided to extend the interval between the first dose of the Pfizer BioNTech and AstraZeneca COVID-19 vaccines from 3 weeks to 12 weeks to maximise the number of people receiving the initial dose, despite the trials only providing vaccine efficacy data based on a schedule of 21 days between doses. This editorial discusses whether there is evidence to support this policy change.


Subject(s)
COVID-19 Vaccines , COVID-19 , Immunogenicity, Vaccine , Vaccination Coverage , Vaccination , COVID-19/epidemiology , COVID-19/immunology , COVID-19/prevention & control , COVID-19 Vaccines/administration & dosage , COVID-19 Vaccines/immunology , Drug Administration Schedule , Evidence-Based Medicine/methods , Evidence-Based Medicine/standards , Government Regulation , Health Policy/legislation & jurisprudence , Humans , Policy Making , SARS-CoV-2 , United Kingdom/epidemiology , Vaccination/methods , Vaccination/standards , Vaccination/statistics & numerical data , Vaccination Coverage/methods , Vaccination Coverage/standards
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